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Reduced small-intestinal injury induced by indomethacin in interleukin-17A-deficient mice

✍ Scribed by Shinya Yamada; Yuji Naito; Tomohisa Takagi; Katsura Mizushima; Yasuko Hirai; Ryusuke Horie; Kohei Fukumoto; Ken Inoue; Akihito Harusato; Naohisa Yoshida; Kazuhiko Uchiyama; Osamu Handa; Takeshi Ishikawa; Hideyuki Konishi; Naoki Wakabayashi; Nobuaki Yagi; Satoshi Kokura; Masakazu Kita; Toshikazu Yoshikawa

Book ID
108953901
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
496 KB
Volume
26
Category
Article
ISSN
0815-9319

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## Abstract ## Objective To examine the capacity of T cell interleukin‐17A (IL‐17A; referred to hereinafter as IL‐17) to induce cartilage damage during experimental arthritis in the absence of IL‐1. ## Methods Local IL‐17 gene transfer was performed in the knee joint of IL‐1–deficient mice and w