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Reduced incidence and severity of collagen-induced arthritis in interleukin-12-deficient mice

✍ Scribed by Kim W. McIntyre; David J. Shuster; Kathleen M. Gillooly; Rajeev R. Warrier; Suzanne E. Connaughton; Leroy B. Hall; Lawrence H. Arp; Maurice K. Gately; Jeanne Magram


Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
663 KB
Volume
26
Category
Article
ISSN
0014-2980

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## Abstract ## Objective To examine the influence of superoxide on the severity of collagen‐induced arthritis (CIA) in mice. ## Methods CIA was induced in DBA/1J mice lacking the extracellular superoxide dismutase (EC‐SOD) gene (knockout [KO]) and in normal DBA/1J mice (wild‐type [WT]). ## Resu