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Collagen-induced arthritis is exacerbated in C-reactive protein–deficient mice

✍ Scribed by Nicholas R. Jones; Melissa A. Pegues; Mark A. McCrory; Steven W. Kerr; Huiping Jiang; Rosemarie Sellati; Valentina Berger; Jorge Villalona; Rajvee Parikh; Mary McFarland; Lynn Pantages; Jeffrey B. Madwed; Alexander J. Szalai


Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
321 KB
Volume
63
Category
Article
ISSN
0004-3591

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## Abstract ## Objective To examine the influence of superoxide on the severity of collagen‐induced arthritis (CIA) in mice. ## Methods CIA was induced in DBA/1J mice lacking the extracellular superoxide dismutase (EC‐SOD) gene (knockout [KO]) and in normal DBA/1J mice (wild‐type [WT]). ## Resu