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Redox regulation of tumor suppressor PTEN in cancer and aging (Review)

✍ Scribed by Matsuda, Satoru

Book ID
120299058
Publisher
Spandidos Publications Ltd
Year
2013
Tongue
English
Weight
444 KB
Volume
31
Category
Article
ISSN
1107-3756

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## Abstract Germline mutations in the tumor‐suppressor gene __PTEN__ (__MMAC1, TEP1__) are found in Cowden syndrome, which predisposes to hamartomas, breast cancer, trichilemmomas, and thyroid tumors of follicular epithelium. __PTEN__ has also been found to be somatically deleted, mutated, and/or s