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Redox regulation of the tumor suppressor PTEN by glutaredoxin 5 and Ycp4

โœ Scribed by Yujeong Kim; Kee-Oh Chay; Inyoung Kim; Yong Bhum Song; Tae-Youl Kim; Seong-Jeong Han; Younghee Ahn; Seung-Hyun Cho; Kwang-Lae Hoe; Bong Whan Ahn; Won-Ki Huh; Seung-Rock Lee

Book ID
116301520
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
788 KB
Volume
407
Category
Article
ISSN
0006-291X

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โœ Vuk Stambolic; Akira Suzuki; Josรฉ Luis de la Pompa; Greg M Brothers; Christine M ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 998 KB

PTEN is a tumor suppressor with sequence homology to protein tyrosine phosphatases and the cytoskeletal protein tensin. mPTEN-mutant mouse embryos display regions of increased proliferation. In contrast, mPTEN-deficient immortalized mouse embryonic fibroblasts exhibit decreased sensitivity to cell d