PTEN is a tumor suppressor with sequence homology to protein tyrosine phosphatases and the cytoskeletal protein tensin. mPTEN-mutant mouse embryos display regions of increased proliferation. In contrast, mPTEN-deficient immortalized mouse embryonic fibroblasts exhibit decreased sensitivity to cell d
✦ LIBER ✦
Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN
✍ Scribed by Vuk Stambolic; Akira Suzuki; José Luis de la Pompa; Greg M Brothers; Christine Mirtsos; Takehiko Sasaki; Jurgen Ruland; Josef M Penninger; David P Siderovski; Tak W Mak
- Book ID
- 117268522
- Publisher
- Elsevier Science
- Year
- 1998
- Tongue
- English
- Weight
- 998 KB
- Volume
- 95
- Category
- Article
- ISSN
- 0092-8674
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