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Effects of Indomethacin on Expression of Pten Tumor Suppressor in Human Cancers

✍ Scribed by Imran Haruna Abdulkareem; Maria Blair

Book ID
118458440
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
112 KB
Volume
8
Category
Article
ISSN
1743-9191

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## Abstract Germline mutations in the tumor‐suppressor gene __PTEN__ (__MMAC1, TEP1__) are found in Cowden syndrome, which predisposes to hamartomas, breast cancer, trichilemmomas, and thyroid tumors of follicular epithelium. __PTEN__ has also been found to be somatically deleted, mutated, and/or s