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Redox-mediated activation of latent transforming growth factor-beta 1

โœ Scribed by Barcellos-Hoff, M. H.


Book ID
120596913
Publisher
Endocrine Society
Year
1996
Tongue
English
Weight
822 KB
Volume
10
Category
Article
ISSN
0888-8809

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Immunocytochemical localization of laten
โœ Hyonkyong Chong; Yoram Vodovotz; George W. Cox; M.H. Barcellos-Hoff ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 773 KB

Transforming growth factor-beta1 (TGF-beta) is secreted in a latent form consisting of mature TGF-beta noncovalently associated with its amino-terminal propeptide, which is called latency associated peptide (LAP). Biological activity depends upon the release of TGF-beta from the latent complex follo