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Transforming growth factor-beta1 inhibits thrombin activation of endothelial cells

✍ Scribed by Harriet Harris; Heide Kirschenlohr; Nicole Szabados; James Metcalfe

Book ID
116397373
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
196 KB
Volume
25
Category
Article
ISSN
1043-4666

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## Abstract Pronounced changes including growth inhibition, increased matrix deposition and suppression of cell‐associated proteolytic activity, take place in endothelial cells (EC) upon the application of TGF‐β. Interrelationships between these effects have shed some light on the mechanism of acti