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Recurrence of Budd-Chiari syndrome after liver transplantation in paroxysmal nocturnal hemoglobinuria

✍ Scribed by Matthias J. Bahr; Jörg Schubert; Jörg S. Bleck; Uwe J.F. Tietge; Bita Boozari; Reinhold E. Schmidt; Jürgen Klempnauer; Christian P. Strassburg; Michael P. Manns


Book ID
110916165
Publisher
Springer
Year
2003
Tongue
English
Weight
643 KB
Volume
16
Category
Article
ISSN
0934-0874

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Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired hemolytic anemia caused by somatic mutations in the phosphatidylinositol glycan-complementation class A gene and the resulting absence of a key complement regulatory protein, CD59. Affected red blood cells in patients with PNH undergo int