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Budd-Chiari syndrome in a patient with paroxysmal nocturnal hemoglobinuria

✍ Scribed by Falchuk, Z. Myron ;Leventhal, B. G.


Book ID
112476244
Publisher
Springer-Verlag
Year
1973
Weight
897 KB
Volume
18
Category
Article
ISSN
0002-9211

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Paroxysmal nocturnal hemoglobinuria (PNH) is a rare, acquired hemolytic anemia caused by somatic mutations in the phosphatidylinositol glycan-complementation class A gene and the resulting absence of a key complement regulatory protein, CD59. Affected red blood cells in patients with PNH undergo int