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Recoil labeling and selective radiation labeling a novel synthesis of propanol-2,3-14C1

✍ Scribed by Shigeru Oae; Carol S. Redvanly; Alfred P. Wolf

Publisher
John Wiley and Sons
Year
1968
Tongue
French
Weight
726 KB
Volume
4
Category
Article
ISSN
0022-2135

No coin nor oath required. For personal study only.

✦ Synopsis

A recoil labeling method for the production of prop~nol-2,3-~~Cl and other simple alcohols is described. In addition propanol-2,3-14C and 2-methyl propanol-3-14C were prepared by the irradiation of methanol solutions of ethylene-14C and propme-1 J4C, respectively, in "scavenger" concentration. This latter approach called selectiveradiation labeling is explored as a method for the preparation of specifically labeled compounds by "non-synthetic" methods. The advantages of selective radiation labeling are : 1. specificity 0-f label; 2. ready control of desired specific activity; 3. eficient use of the labeling isotope in an appropriate precursor; 4. ease of purification and isolation of products; 5. minimum labor. Any source of penetrating radiation can be used in selective radiation labeling.

&COIL LABELING.

* Research performed under the auspices of the U. S. Atomic Energy Commission.

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