Recognition of distinct epitopes on the HLA-A2 antigen by cytotoxic T lymphocytes
β Scribed by van der Poel, Jan J.; Pool, Jos; Goulmy, Els; Giphart, Marius J.; van Rood, Jon J.
- Book ID
- 122642411
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 643 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0198-8859
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
A comprehensive analysis of human alloimmune cytotoxic T lymphocytes (CTLs) specific for the HLA-A2 antigen identified 11% of HLA-A2 positive cells as outliers. In total, 11 unrelated serologically indistinguishable, but distinguishable by cell-mediated lympholysis (CML) HLA-A2 positive outlier cell
Human alloimmune cytotoxic T cells, sensitized selectively against the HLA-A2 antigen, were tested on a panel of selected target cells. Five HLA-A2 positive outlier cells could be identified. These outlier cells were only weakly lysed by HLA-A2 specific CTLs, although they were serologically indisti
## Abstract Tieβ2 stabilises pericyteβendothelial interactions during angiogenesis and is highly expressed on endothelium during several diseases, including arthritis, ageβrelated macular degeneration and cancer. A vaccine that targets endothelium overexpressing Tieβ2 may result in vessel damage an