Synthesis of ethyl N-(diphenyl)methyl-1,
β
Eugene A Mash; Lawrence J Williams; Steven S Pfeiffer
π
Article
π
1997
π
Elsevier Science
π
French
β 187 KB
A concise method for the synthesis of 1,2,3,4-tetrahydroisoquinoline-3-earboxylic acid derivatives from ot,tx'-dibromo-o-xylenes via sequential C-alkylation and N-alkylation of a glycine anion is described.