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Efficient synthesis of methyl (+)-(1S,3R)-3-(2,2-dimethoxycarbonylethyl)-2,2-dimethylcyclopropane-1-carboxylate from (+)-4α-acetyl-2-carene

✍ Scribed by F. Z. Makaev


Book ID
105595570
Publisher
Springer
Year
2000
Tongue
English
Weight
121 KB
Volume
49
Category
Article
ISSN
1573-9171

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Shikimic acid (~-1) was first isolated from the oriental plant Illicium religiosum (in Japanese, shikimi) in 1885 by Eijkma&. After nearly 50 years, thanks to the pioneering works of Fischer and Dangschat4 during the 1930's, the complete structure and absolute stereochemistry of this acid were estab