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Synthesis of ethyl N-(diphenyl)methyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylates

✍ Scribed by Eugene A Mash; Lawrence J Williams; Steven S Pfeiffer

Publisher
Elsevier Science
Year
1997
Tongue
French
Weight
187 KB
Volume
38
Category
Article
ISSN
0040-4039

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✦ Synopsis

A concise method for the synthesis of 1,2,3,4-tetrahydroisoquinoline-3-earboxylic acid derivatives from ot,tx'-dibromo-o-xylenes via sequential C-alkylation and N-alkylation of a glycine anion is described.

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