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Rapid31P NMR test of liver function

✍ Scribed by William J. Thoma; Kâmil Uǧurbil

Publisher: John Wiley and Sons
Year: 1988
Tongue: English
Weight: 213 KB
Volume: 8
Category: Article
ISSN: 0740-3194
DOI: 10.1002/mrm.1910080212

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✦ Synopsis

The 31P NMR spectrum of perfused rat liver was found to be dependent on the exogenous carbon available to the tissue. When pyruvate was supplied to liver initially perfused with lactate, Pi decreased, phosphoenol pyruvate and phosphomonoesters increased, and nucleotide pools remained the same. It is proposed that these changes can be used to evaluate liver function.

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