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Rapamycin synthetic studies. 1. Construction of the C(27)-C(42) subunit

โœ Scribed by Amos B. Smith III; Stephen M. Condon; John A. McCauley; James W. Leahy; Johnnie L. Leazer Jr.; Robert E. Maleczka Jr.


Publisher
Elsevier Science
Year
1994
Tongue
French
Weight
399 KB
Volume
35
Category
Article
ISSN
0040-4039

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Spongistatin synthetic studies. 3. Const
โœ Amos B. Smith III; Quyan Lin; Kiyoshi Nakayama; Armen M. Boldi; Christopher S. B ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 218 KB

A convergent synthesis of the C(1-17) AB-ring subunit of the spongistatins, exceedingly scarce and highly ant]mitotic polyether macrolides, has been achieved via a one-flask dithiane bisalkylation, stereocontrolled spiroketalization, and Julia sulfone coupling/methylenation. ยฉ ]997 Elsevier Science