Radiotherapy for Bony Manifestations of Langerhans Cell Histiocytosis
β Scribed by Thomas Olschewski; Michael Heinrich Seegenschmiedt
- Publisher
- Springer
- Year
- 2006
- Tongue
- German
- Weight
- 380 KB
- Volume
- 182
- Category
- Article
- ISSN
- 0179-7158
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Background. Langerhans' cell histiocytosis (LCH) is an uncommon, poorly understood granulomatous disease, characterized by the idiopathic proliferation of Langerhan's cells or their marrow precursors. In 1985, the Philadelphia Workshop adopted the term "Langerhans' cell histiocytosis" (LCH) to diffe
A 3-month-old male infant presented with pallor, hepatomegaly (4.5 cm), splenomegaly (1.5 cm), anaemia (Hb 6 g/dl) and thrombocytopenia (16 X 10(9)/l). A liver biopsy was diagnostic for Langerhans cell histiocytosis (histiocytosis X). The patient's lymphocytes, co-cultured with neonatal lymphocytes,