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Radiosynthesis of high specific activity tritium-labeled precocene II

✍ Scribed by William S. Bowers; Lothar Franke; David M. Soderlund

Publisher: John Wiley and Sons
Year: 1983
Tongue: French
Weight: 244 KB
Volume: 20
Category: Article
ISSN: 0022-2135
DOI: 10.1002/jlcr.2580200703

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✦ Synopsis

The i n s e c t a n t i j u v e n i l e hormone precocene I1 (6,7-dimethoxy-2,2dimethylchrornene) was r a d i o s y n t h e s i z e d , i n c o r p o r a t i n g t r i t i u m s p e c i f i c a l l y i n t h e gem-dimethyl group a t h i g h s p e c i f i c a c t i v i t y .

Hydroxycoumarin was methylated (CH I / K O H ) and t h e n o x i d i z e d a t 6p o s i t i o n (K2S208/NaOH).

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