Quaternization of 1,2-disubstituted 6,7-dimethoxy-1,2,3,4-tetrahydroiso-quinolines
✍ Scribed by G. Bernáth; J. Kóbor; K. Koczka; L. Radics; Maria Kajtár
- Publisher
- Elsevier Science
- Year
- 1968
- Tongue
- French
- Weight
- 276 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0040-4039
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✦ Synopsis
Quaternization of N-alkyl heterocycles has been extensively studied in several laboratories in order to obtain informations on the conformational properties of hetcro rings on one hand (l), and to elucidate the mechanism, steric course and kinetics of quaternization process on the other (2). With
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## Abstract Some 6,7‐dimethoxy‐1‐halobenzyl‐1,2,3,4‐tetrahydroisoquinolines were synthesized from 2‐(3,4‐dimethoxyphenyl)ethylamine and halophenylacetic acids in three steps in good yield.
Z u s a m m e nf a s sung. Aus Eleutherine bulbosa wurde in kleiner Menge ein neuer Pflanzemtoff, Zleutherinol, isoliert. Eleutherinol-dimethylather lieferte bei der alkalischen Spaltung neben Essigsaure und Aceton l-Acetyl-2oxy-3-methyl-6,8-dimethoxy-nap htaLin und 2-Oxy-3 -methyl-64-d imethoxy-na