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Quantitative measurements of proton spin-lattice (T1) and spin–spin (T2) relaxation times in the mouse brain at 7.0 T

✍ Scribed by David N. Guilfoyle; Victor V. Dyakin; Jacqueline O'Shea; Gaby S. Pell; Joseph A. Helpern

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
382 KB
Volume
49
Category
Article
ISSN
0740-3194

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✦ Synopsis

The goal of this work is to provide regional T(1) and T(2) values at a field strength of 7 T for the normal mouse brain at 6 weeks and 1 year old. A novel segmented snapshot FLASH sequence was used to measure T(1) in the hippocampus, corpus callosum, and the retrosplenial granular (RSG) cortex; T(2) measurements were made in the same regions using a single spin echo sequence repeated at six separate echo times. Both T(1) and T(2) measurements were validated with phantom measurements.

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