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Quantitative estimations of the contribution of different bile acid pathways to total bile acid synthesis in the rat

✍ Scribed by ZR Vlahcevic; RT Stravitz; DM Heuman; PB Hylemon; WM Pandak


Book ID
118519722
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
381 KB
Volume
113
Category
Article
ISSN
0016-5085

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During biosynthesis of bile acid, carbons 25-26-27 are removed from the cholesterol side chain. Side-chain oxidation begins either with hydroxylation at the 26-position, in which case the three-carbon fragment is released as propionic acid, or with hydroxylation at the 25-position, in which case the