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Clofibrate reduces bile acid synthesis and amplifies the pathway for the formation of ?22-bile acids

✍ Scribed by SETCHELL, K


Book ID
122486139
Publisher
John Wiley and Sons
Year
1995
Tongue
English
Weight
158 KB
Volume
22
Category
Article
ISSN
0270-9139

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πŸ“œ SIMILAR VOLUMES


Regulation of bile acid synthesis. II. E
✍ Douglas M. Heuman; Z. Reno Vlahcevic; Marsha L. Bailey; Phillip B. Hylemon πŸ“‚ Article πŸ“… 1988 πŸ› John Wiley and Sons 🌐 English βš– 761 KB

Bile acid synthesis is believed to be regulated by bile salts returning to the liver via the portal vein and suppressing cholesterol 7a-hydroxylase, the rate-limiting enzyme in the bile acid biosynthesis pathway. In order to characterize the relative effectiveness of bile salts in regulating bile ac