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Quantitative assessment of the influence of CYP1B1 polymorphisms and head and neck squamous cell carcinoma risk

✍ Scribed by Shen, Ming; Hu, Yuan-Yuan; Hu, Yu-Kun; Xie, Long-Chuan; Xu, Xiao-Ming; Wu, Ming-Yue; Niu, Yu-Ming

Book ID: 121588522
Publisher: S. Karger AG
Year: 2013
Tongue: English
Weight: 247 KB
Volume: 35
Category: Article
ISSN: 1010-4283
DOI: 10.1007/s13277-013-1516-2

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Differences in genetic susceptibility to tobacco-induced carcinogenesis appear to modulate an individual's risk of squamous-cell carcinoma of the head and neck (SCCHN). Risk for SCCHN may be associated with the null alleles of the carcinogen-metabolizing genes glutathione-S-transferase (GST) T1 and