CYP1A1,GSTM1andGSTT1polymorphisms, tobacco and alcohol status and risk of head and neck squamous cell carcinoma
✍ Scribed by Gustavo Jacob Lourenço; Erika Furquim Soledade Neves Silva; José Augusto Rinck-Junior; Carlos Takahiro Chone; Carmen Silvia Passos Lima
- Book ID
- 107693982
- Publisher
- S. Karger AG
- Year
- 2011
- Tongue
- English
- Weight
- 138 KB
- Volume
- 32
- Category
- Article
- ISSN
- 1010-4283
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📜 SIMILAR VOLUMES
## Abstract ## Background. Alcohol intake and tobacco smoke, in addition to other environmental and genetic factors, have been associated with head and neck cancer. We evaluated the role of metabolic enzyme polymorphisms on the risk of head and neck cancer in a hospital‐based case‐control study.
We investigated the genetic polymorphisms of CYP1A1, CYP2E1 and GSTM1 in Japanese esophageal cancer patients (n = 53) with a histological diagnosis of squamous-cell carcinoma, to determine whether susceptibility to esophageal cancer is associated with these polymorphisms. There were no significant d