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Quantitative assessment of the association between TP53 Arg72Pro polymorphism and risk of glioma

โœ Scribed by Zhang, Feng; Li, Danni; Li, Yanshuang; Li, Haixia; Sun, Jinbo; Li, Xianfeng; Li, Xiaohong

Book ID
121561881
Publisher
S. Karger AG
Year
2013
Tongue
English
Weight
258 KB
Volume
35
Category
Article
ISSN
1010-4283

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## Abstract It is well known that the TP53 gene considerably influences on DNA repair processes. Polymorphisms in the TP53 gene, particularly the wellโ€known Arg72Pro in codon 72 of exon 4 (Ex4+119 G>C; rs1042522), can modify the functionality of the p53 protein and activation of DNA repair. Actuall