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Association between TP53 gene Arg72Pro polymorphism and idiopathic infertility in southeast Chinese Han males

โœ Scribed by Jin, Qi; Wang, Binbin; Wang, Jing; Liu, Tao; Yu, Xiaoying; Jia, Chao; Fang, Xiang; Peng, Yifeng; Ma, Xu

Book ID
125507582
Publisher
Informa plc
Year
2013
Tongue
English
Weight
150 KB
Volume
59
Category
Article
ISSN
1939-6368

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## Abstract It is well known that the TP53 gene considerably influences on DNA repair processes. Polymorphisms in the TP53 gene, particularly the wellโ€known Arg72Pro in codon 72 of exon 4 (Ex4+119 G>C; rs1042522), can modify the functionality of the p53 protein and activation of DNA repair. Actuall