Quantitative assessment of the association between TP53 Arg72Pro polymorphism and bladder cancer risk
β Scribed by Zhi-Hong Liu, Er-Dun Bao
- Book ID
- 120751468
- Publisher
- Springer
- Year
- 2012
- Tongue
- English
- Weight
- 265 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0301-4851
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## Abstract It is well known that the TP53 gene considerably influences on DNA repair processes. Polymorphisms in the TP53 gene, particularly the wellβknown Arg72Pro in codon 72 of exon 4 (Ex4+119 G>C; rs1042522), can modify the functionality of the p53 protein and activation of DNA repair. Actuall
## Abstract No clear consensus has been reached on the __TP53__ Arg72Pro polymorphism (G12139C) and lung cancer risk. Thus, a metaβanalysis was conducted to summarize the possible association. There was no statistical association between 12139C (Pro allele) and lung cancer risk in Caucasians compar