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TP53 Arg72Pro Polymorphism and Skin Cancer Risk: A Meta-Analysis

✍ Scribed by Jiang, De-Ke; Wang, Wen-Zhang; Ren, Wei-Hua; Yao, Lei; Peng, Bo; Yu, Long


Book ID
109875563
Publisher
Nature Publishing Group
Year
2011
Tongue
English
Weight
213 KB
Volume
131
Category
Article
ISSN
0022-202X

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## Abstract No clear consensus has been reached on the __TP53__ Arg72Pro polymorphism (G12139C) and lung cancer risk. Thus, a meta‐analysis was conducted to summarize the possible association. There was no statistical association between 12139C (Pro allele) and lung cancer risk in Caucasians compar

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## Abstract Arg72Pro is a common polymorphism in __TP53,__ showing differences in its biological functions. Case‐control studies have been performed to elucidate the role of Arg72Pro in cancer, although the results are conflicting and heterogeneous. Here, we analyzed pooled data from case‐control s