𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Quantitation of Pyridylhydroxybutyl-DNA Adducts in Liver and Lung of F-344 Rats Treated with 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone and Enantiomers of Its Metabolite 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol

✍ Scribed by Upadhyaya, Pramod; Kalscheuer, Stephen; Hochalter, J. Bradley; Villalta, Peter W.; Hecht, Stephen S.

Book ID
126034349
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
599 KB
Volume
21
Category
Article
ISSN
0893-228X

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Genetic variability in the metabolism of
Genetic variability in the metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL)
✍ Monica Ter-Minassian; Kofi Asomaning; Yang Zhao; Feng Chen; Li Su; Steven G. Car πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 French βš– 354 KB

## Abstract Urinary metabolites of the tobacco‐specific nitrosamine 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanone (NNK), 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanol (NNAL) and its glucuronides, termed total NNAL, have recently been shown to be good predictors of lung cancer risk, years before di

Synthesis of 4- (methylnitrosamino)-1- (
Synthesis of 4- (methylnitrosamino)-1- (3-pyridyl)-1-butanone, 4- (carbethoxynitrosamino)-1- (3-pyridyl)-1-butanone, and Nβ€² -nitrosonornicotine labelled with tritium in the pyridine ring
✍ James C. Wiley Jr.; David H. T. Chien; Nancy A. Nungesser; Dorothy Lin; Stephen πŸ“‚ Article πŸ“… 1988 πŸ› John Wiley and Sons 🌐 French βš– 349 KB

The carcinogenic tobacco-specif ic nitrosamines 4- (methylnitrosemino) -1-(3-pyridyl) -1-butanone (NNK) and N'-nitrosonornicotine (NNN), as well as the model compound 4-(carbethoxynitrosamino) -1-(3-pyridyl) -1butanone, were synthesized with tritium at the 5-position of the pyridine ring. In each c