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Quantitation of a new cholecystokinin and gastrin receptor antagonist (L-365,260) in dog and rat plasma by high-performance liquid chromatography

โœ Scribed by I.-Wu Chen; Juinn H. Lin; Joan Dorley


Book ID
107996947
Publisher
Elsevier Science
Year
1992
Weight
311 KB
Volume
576
Category
Article
ISSN
0378-4347

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0 A high-performance liquid chromatographic procedure was developed for the determination of diltiazem and desacetyldiltiazem in dog plasma. Two milliliters of plasma is extracted with a hexane-2-propanol mixture. The assay uses a reverse-phase column maintained at 55ยฐC with a silica saturation colu