Determination of L-365,260, a new cholecystokinin receptor (CCK-B) antagonist, in plasma by liquid chromatography/atmospheric pressure chemical ionization mass spectrometry
β Scribed by J. D. Gilbert; E. L. Hand; A. S. Yuan; T. V. Olah; T. R. Covey
- Book ID
- 102775850
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 501 KB
- Volume
- 21
- Category
- Article
- ISSN
- 1076-5174
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
L-654,066 is a new 5 alpha-reductase inhibitor. A sensitive and specific assay based on combined liquid chromatography/mass spectrometry has been developed for the determination of this drug candidate in plasma. The analyte was isolated from plasma by solid-phase extraction on a C-18 cartridge. A re
## Abstract A multiβresidue gradient liquid chromatographic (LC) separation was developed for five Ξ²βagonists (fenoterol, metaproterenol, terbutaline, salbutamol and clenbuterol) in human plasma and detection was made using LC/atmospheric pressure chemical ionization mass spectrometry (LC/APCIβMS)