Pyrimidine derivatives from 1-aroyl-4,5-diamino-4,5-dihydro-imidazoles: A new ring expansion
✍ Scribed by Luisa Citerio; Michele Garufi; Riccardo Stradi
- Publisher
- Elsevier Science
- Year
- 1978
- Tongue
- French
- Weight
- 187 KB
- Volume
- 19
- Category
- Article
- ISSN
- 0040-4039
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## Abstract magnified image The 7‐aryl‐4,7‐dihydro[1,2,4]triazolo[1,5‐__a__]pyrimidines **1a**, **1b**, **1c** can undergo addition of hydrazine to the enamine double bond leading to hydrazine derivatives of tetrahydrotriazolopyrimidines **2a**, **2b**, **2c**; the process is usually accompanied by
## Abstract magnified image The reaction of 3‐amino‐1,2,4‐triazole (**1**) with arylidene‐5‐acetyl barbituric acid (**2b**, **2c**) or dehydroacetic acid (**2a**) by refluxing in butanol leads to the formation of dihydro‐1,2,4‐triazolo[1,5‐__a__]pyrimidines **3a**, **3b**, **3c**. J. Heterocyclic
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