New dihydro-1,2,4-triazolo[1,5-a]pyrimidines based on arylidene derivatives of 5-acetylbarbituric and dehydroacetic acids
โ Scribed by Roman V. Rudenko; Sergey A. Komykhov; Vladimir I. Musatov; Sergey M. Desenko
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2009
- Tongue
- English
- Weight
- 162 KB
- Volume
- 46
- Category
- Article
- ISSN
- 0022-152X
- DOI
- 10.1002/jhet.81
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โฆ Synopsis
Abstract
magnified image
The reaction of 3โaminoโ1,2,4โtriazole (1) with arylideneโ5โacetyl barbituric acid (2b, 2c) or dehydroacetic acid (2a) by refluxing in butanol leads to the formation of dihydroโ1,2,4โtriazolo[1,5โa]pyrimidines 3a, 3b, 3c. J. Heterocyclic Chem., 46, 285 (2009).
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## Abstract magnified image The 7โarylโ4,7โdihydro[1,2,4]triazolo[1,5โ__a__]pyrimidines **1a**, **1b**, **1c** can undergo addition of hydrazine to the enamine double bond leading to hydrazine derivatives of tetrahydrotriazolopyrimidines **2a**, **2b**, **2c**; the process is usually accompanied by
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a โFull Textโ option. The original article is trackable v
## Abstract A series of novel 1โphenylthieno[1,2,4]triazolo[4,3โ__a__]pyrimidinโ5(4__H__)โone derivatives **5** and **6** were synthesized by oxidative cyclization of thienopyrimidinonyl hydrazones using iodobenzene diacetate. J. Heterocyclic Chem., (2011).