𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Pyrazino[2,3-c][1,2,6]thiadiazine 2,2-dioxides. Sulfur dioxide analogs of pteridines

✍ Scribed by Pilar Goya; Juan Antonio Paez; Wolfgang Pfleiderer

Book ID
112127498
Publisher
Journal of Heterocyclic Chemistry
Year
1984
Tongue
English
Weight
233 KB
Volume
21
Category
Article
ISSN
0022-152X

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Unconventional Alkoxylation of Pyrazino[
Unconventional Alkoxylation of Pyrazino[2,3-c][1,2,6]thiadiazine 2,2-Dioxides Mediated by N-Halosuccinimides
✍ Nuria Campillo; JuanΒ A. PΓ‘ez; Pilar Goya πŸ“‚ Article πŸ“… 2002 πŸ› John Wiley and Sons 🌐 English βš– 74 KB πŸ‘ 1 views

One pot alkoxylation at position 7 of 6-arylpyrazino [2,3c][1,2,6]thiadiazine 2,2-dioxides with NBS or NCS in the appropriate alcohol is described. Rationalization of the mechanism of the reaction, which does not proceed through the in-

Pyrazino[2,3-c]-1,2,6-thiadiazine 2,2-di
Pyrazino[2,3-c]-1,2,6-thiadiazine 2,2-dioxides. Synthesis of SO2 analogues of folic acid antagonists
✍ Alkorta, Ibon ;Goya, Pilar ;PΓ‘ez, Juan Antonio ;PΓ©rez, ConcepciΓ³n πŸ“‚ Article πŸ“… 1991 πŸ› John Wiley and Sons 🌐 English βš– 239 KB

## Abstract The synthesis of novel analogues of foric acid (FA) antagonists derived from the pyrazino[2,3‐c]‐1,2,6‐thiadiazine 2,2‐dioxide system incorporating the glutamic acid side chain at the 7‐position is described. No significant DHFR inhibition of cytotoxic activity has been found with these