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Purification and Crystallization of Human Cyclin-dependent Kinase 2

✍ Scribed by Jody Rosenblatt; Hendrik De Bondt; Jarmila Jancarik; David O. Morgan; Sung-Hou Kim

Book ID
115625990
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
166 KB
Volume
230
Category
Article
ISSN
0022-2836

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Purification and crystallization of cycl
Purification and crystallization of cyclin-dependent kinase inhibitor p21
✍ Dale R. Mayrose; Hengming Ke; Yue Xiong; Michael A. Nichols πŸ“‚ Article πŸ“… 1996 πŸ› Cold Spring Harbor Laboratory Press 🌐 English βš– 343 KB

## Abstract p21, a universal inhibitor of mammalian cyclin‐dependent kinases (CDK), regulates cell cycle progression by forming various distinct protein complexes with cyclins, CDKs, and the proliferating cell nuclear antigen. We have overexpressed recombinant human p21 in __E. coli__ and purified