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Cyclin-dependent kinase inhibitors: the age of crystals

✍ Scribed by Jonathon Pines


Book ID
114222912
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
116 KB
Volume
1332
Category
Article
ISSN
0304-419X

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## Abstract p21, a universal inhibitor of mammalian cyclin‐dependent kinases (CDK), regulates cell cycle progression by forming various distinct protein complexes with cyclins, CDKs, and the proliferating cell nuclear antigen. We have overexpressed recombinant human p21 in __E. coli__ and purified