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Purification and characterization of Erythroid Differentiation Factor(EDF) isolated from human leukemia cell line THP-1

✍ Scribed by Yuzuru Eto; Tomoko Tsuji; Misako Takezawa; Satoshi Takano; Yasunori Yokogawa; Hiroshiro Shibai


Book ID
115760953
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
442 KB
Volume
142
Category
Article
ISSN
0006-291X

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## Abstract A human leukemic cell line (THP‐1) cultured from the blood of a boy with acute monocytic leukemia is described. This cell line had Fc and C3b receptors, but no surface or cytoplasmic immunoglobulins. HLA haplotypes of THP‐1 were HLA‐A2, ‐A9, ‐B5, ‐DRW1 and ‐DRW2. The monocytic nature of