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Purification and characterization of human colony-stimulating factor 1 from human pancreatic carcinoma (MIA PaCa-2) cells

✍ Scribed by Jae-Hung Shieh; John K. Cini; Ming-Chi Wu; Adel A. Yunis

Book ID
115707612
Publisher
Elsevier Science
Year
1987
Tongue
English
Weight
822 KB
Volume
253
Category
Article
ISSN
0003-9861

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## Abstract We found that 12‐__O__‐tetradecanoylphorbol‐13‐acetate (TPA) promoted anchorage‐independent growth but did not affect anchorage‐dependent growth of MIA PaCa‐2 human pancreatic carcinoma cells. TPA markedly activated mitogen‐activated protein kinase (MAPK)/extracellular signal–regulated