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Proton NMR imaging of cerebral blood flow using H217O

✍ Scribed by K. K. Kwong; A. L. Hopkins; J. W. Belliveau; D. A. Chesler; L. M. Porkka; R. C. McKinstry; D. A. Finelli; G. J. Hunter; J. B. Moore; R. G. Barr; B. R. Rosen

Publisher: John Wiley and Sons
Year: 1991
Tongue: English
Weight: 313 KB
Volume: 22
Category: Article
ISSN: 0740-3194
DOI: 10.1002/mrm.1910220116

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Cerebral blood flow was quantitatively mapped by monitoring the cerebral washout of H~2~ ^17^O using rapid, single‐shot proton NMR imaging. H~2~ ^17^O acts as a freely diffusible contrast agent for proton imaging via its scalar‐coupled term, enhancing T~2~ relaxation. Measured values for CBF ranged from 29 to 106 ml/min/100 g over a range of arterial pCO~2~ between 23 and 81 Torr. © 1991 Academic Press, Inc.

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