✦ LIBER ✦

In Vivo measurement of cerebral oxygen consumption and blood flow using 17O magnetic resonance imaging

✍ Scribed by J. Pekar; L. Ligeti; Z. Ruttner; R. C. Lyon; T. M. Sinnwell; P. van Gerderen; D. Fiat; C. T. W. Moonen; A. C. McLaughlin

Publisher: John Wiley and Sons
Year: 1991
Tongue: English
Weight: 390 KB
Volume: 21
Category: Article
ISSN: 0740-3194
DOI: 10.1002/mrm.1910210217

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

We used ^17^O NMR imaging techniques to measure the H~2~^17^O concentration in a 0.8‐ml voxel in the cat brain following injection of an arterial bolus of enriched H~2~^17^O and during inhalation of enriched ^17^O~2~. We also measured the H~2~^17^O concentration in arterial blood during ^17^O~2~ inhalation. The data from the first measurement were used to calculate the blood flow in the voxel. The data from all three measurements were combined to calculate the oxygen consumption in the voxel. The values of cerebral blood flow and oxygen consumption calculated with ^17^O NMR techniques agree reasonably well with values calculated for a similar region of the cat brain using autoradiographic techniques. © 1991 Academic Press, Inc.

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