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Proteolytic processing of the p75 neurotrophin receptor: A prerequisite for signalling?

✍ Scribed by S. Skeldal; D. Matusica; A. Nykjaer; E. J. Coulson

Book ID
112009657
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
22 KB
Volume
34
Category
Article
ISSN
0265-9247

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The recent recognition that the p75 neurotrophin receptor, p75 NTR , can induce apoptotic signals has contributed to the perception that it acts primarily as a death receptor. Although the molecular mechanisms of p75 NTR signaling remain to be fully characterized, many of the currently identified pa