Synovial fluids from 6 of 12 patients with rheumatoid arthritis (RA) and from 3 of 11 patients with reactive arthritis contained measurable levels of tumor necrosis factor a (TNFa). Seven of 12 sera from RA patients contained TNFa, while only 1 of those from reactive arthritis patients was positive.
✦ LIBER ✦
Protein metabolism in rheumatoid arthritis and aging. Effects of muscle strength training and tumor necrosis factor α
✍ Scribed by Laura C. Rall; Clifford J. Rosen; Gregory Dolnikowski; Wilburta J. Hartman; Nancy Lundgren; Leslie W. Abad; Charles A. Dinarello; Ronenn Roubenoff
- Publisher
- John Wiley and Sons
- Year
- 1996
- Tongue
- English
- Weight
- 934 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0004-3591
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## Objective: To investigate the regulation of expression of the angiogenic cytokine vascular endothelial growth factor (vegf) in rheumatoid arthritis (ra), in order to determine whether new blood vessel formation could be a potential therapeutic target in ra. ## Methods: Dissociated ra synovial