CK2 is a pleiotropic, ubiquitous, and constitutively active protein kinase (PK), with both cytosolic and nuclear localization in most mammalian cells. The holoenzyme is generally composed of two catalytic (alpha and/or alpha') and two regulatory (beta) subunits, but the free alpha/alpha' subunits ar
โฆ LIBER โฆ
Protein kinase CK2 as a druggable target
โ Scribed by Sarno, Stefania; Pinna, Lorenzo A.
- Book ID
- 119968368
- Publisher
- Royal Society of Chemistry
- Year
- 2008
- Tongue
- English
- Weight
- 184 KB
- Volume
- 4
- Category
- Article
- ISSN
- 1742-206X
- DOI
- 10.1039/B805534C
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
How druggable is protein kinase CK2?
โ
Giorgio Cozza; Andrea Bortolato; Stefano Moro
๐
Article
๐
2009
๐
John Wiley and Sons
๐
English
โ 938 KB
ChemInform Abstract: How Druggable Is Pr
โ
Giorgio Cozza; Andrea Bortolato; Stefano Moro
๐
Article
๐
2010
๐
John Wiley and Sons
โ 15 KB
Validation of protein kinase CK2 as onco
โ
S. Seeber; O. G. Issinger; T. Holm; L. P. Kristensen; B. Guerra
๐
Article
๐
2005
๐
Springer
๐
English
โ 913 KB
Emergence of protein kinase CK2 as a key
โ
Janeen H. Trembley; Zhong Chen; Gretchen Unger; Joel Slaton; Betsy T. Kren; Cart
๐
Article
๐
2010
๐
IOS Press
๐
English
โ 299 KB
Protein kinases CK1 and CK2 as new targe
โ
Daniel I. Perez; Carmen Gil; Ana Martinez
๐
Article
๐
2010
๐
John Wiley and Sons
๐
English
โ 310 KB
## Abstract Following the discovery of the human kinome, protein kinases have become the second most important group of drug targets as they can be modulated by small ligand molecules. Moreover, orally active protein kinase inhibitors have recently reached the market and there are many more in clin
Protein kinase CK2
โ
Lorenzo A. Pinna
๐
Article
๐
1997
๐
Elsevier Science
๐
English
โ 328 KB