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Protein kinase CK2

✍ Scribed by Lorenzo A. Pinna

Book ID: 117756286
Publisher: Elsevier Science
Year: 1997
Tongue: English
Weight: 328 KB
Volume: 29
Category: Article
ISSN: 1357-2725
DOI: 10.1016/s1357-2725(96)00142-2

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CK2 is a pleiotropic, ubiquitous, and constitutively active protein kinase (PK), with both cytosolic and nuclear localization in most mammalian cells. The holoenzyme is generally composed of two catalytic (alpha and/or alpha') and two regulatory (beta) subunits, but the free alpha/alpha' subunits ar