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Protein Engineering: Modified Hemoglobin as a Blood Substitute

✍ Scribed by Dr. Timm-H. Jessen; Dr. Rolf Hilgenfeld


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
265 KB
Volume
31
Category
Article
ISSN
0044-8249

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πŸ“œ SIMILAR VOLUMES


Stable preservation of hemoglobin vesicl
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Long-term preservation of hemoglobin (Hb) vesicles, the so-called artificial red cell (ARC), in dry powder was studied. Carbonylhemoglobin (COHb) was encapsulated in the vesicle of 1,2-bis(2,4-octadecadienoyl)-sn-glycero-3-phosphocholine (DODPC) and the polymerizable membrane components were polymer

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✍ Dellacherie, E. ;LΓ©onard, M. πŸ“‚ Article πŸ“… 1985 πŸ› Wiley (John Wiley & Sons) βš– 140 KB

Hemoglobin (Hb) i n solution is capable of transporting oxygen and could thus be considered as an ideal red cell substitute. However, i t presents two important drawbacks : a short vascular retention time and a high oxygen affinity. Chemical modifications