## Abstract Mutations in parkin are the second most common known cause of Parkinson's disease (PD). Parkin is an ubiquitin E3 ligase that monoubiquitinates and polyubiquitinates proteins to regulate a variety of cellular processes. Loss of parkin's E3 ligase activity is thought to play a pathogenic
β¦ LIBER β¦
Protein aggregation in the pathogenesis of familial and sporadic Parkinson's disease
β Scribed by Kevin St. P. McNaught; C. Warren Olanow
- Book ID
- 116780787
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 395 KB
- Volume
- 27
- Category
- Article
- ISSN
- 0197-4580
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