## SO great efforts in prostaglandin syntheses have been currently made on the synthesis of novel prostaglandin analogues and on much more convenient synthetic approach to these compounds. Recently, the conjugate addition-enolate trapping method has been used for the short and highly convergent ap
Prostaglandins - a new total synthesis of (±)-11-deoxyprostaglandins
✍ Scribed by M.P.L. Caton; E.C.J. Coffee; G.L. Watkins
- Publisher
- Elsevier Science
- Year
- 1972
- Tongue
- French
- Weight
- 90 KB
- Volume
- 13
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
In addition to their interesting pharmacological properties, 2.3,4 the desoxyprostaglandins are also potentially important intermediates for conversion into the naturally occurring prostaglandins via microbiological hydroxylation. The recent report5 of an improved synthesis of an important intermedi
In an earlier communication ' from our laboratory we reported the total synthesis of a physiologically active analogue (V) of prostaglandin. The ssymmetric centres C-8, C-9 and C-l.2 were assumed to have configurations shown in the formula. In this communication, we report an improved synthesis and