In cloned osteoblast-like cells, MC3T3-EII prostaglandin F, , (PGF,,) stimulated arachidonic acid (AA) release in a dose-dependent manner in the range between 1 n M and 10 pM. 12-O-tetradecanoylphorbol-l3-acetate (TPA), a protein kinase C (PKC) activator, which by itself had little effect on AA rele
Prostaglandin-Induced changes in calcium uptake and cAMP production in osteoblast-like cells: Role of protein kinase C
β Scribed by S. Hagel-Bradway; D. N. Tatakis; R. Dziak
- Book ID
- 110554800
- Publisher
- Springer
- Year
- 1991
- Tongue
- English
- Weight
- 549 KB
- Volume
- 48
- Category
- Article
- ISSN
- 1432-0827
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Prostaglandin E, (PGE,) is an important local regulator in bone. The present study was performed to investigate the effect of PGE, on osteoclast-like cell formation and bone-resorbing activity of mature osteoclasts in the presence or absence of osteoblasts. PGE, ( M) significantly stimulated osteocl
## Abstract We previously reported that prostaglandin F~2Ξ±~ (PGF~2Ξ±~) receptor is coupled to pertussis toxin (PTX)βsensitive GTPβbinding protein (G protein) in osteoblastβlike MC3T3βE1 cells [Miwa et al. (1990): Biochem Biophys Res Commun 171:1229β1235]. In the present study, we examined the effect